The Association between VDR Gene Polymorphisms and Diabetic Retinopathy Susceptibility: A Systematic Review and Meta-Analysis

Table 2

Genotype frequencies of VDR polymorphisms in 7 studies included in this systematic review and meta-analysis.

Author	Genotype frequencies		Allele frequencies		P-HWE
	Case	Control	Case	Control
FokI	FF/Ff/ff	FF/Ff/ff	F/f	F/f
Zhong et al.	11/53/30	35/61/14	75/113	131/89	0.113
Hou et al.	10/40/112	12/34/46	60/264	58/126	0.167
Wu et al.	6/37/19	21/35/12	49/75	77/59	0.694
Bućan et al.	6/9/4	7/15/6	21/17	29/27	0.700
Cyganek et al.	20/45/20	51/93/38	85/85	195/169	0.713
Taverna et al.	38/65/23	57/56/15	141/111	170/86	0.826
BsmI	Bb/Bb/bb	Bb/Bb/bb	B/b	B/b
Zhong et al.	5/27/62	6/27/77	37/151	39/181	0.096
Bućan et al.	2/10/7	5/16/7	14/24	26/30	0.431
Cyganek et al.	10/37/38	21/84/77	57/113	126/238	0.791
TaqI	TT/Tt/tt	TT/Tt/tt	T/t	T/t
Bućan et al.	7/8/4	11/12/5	22/16	34/22	0.591
Cyganek et al.	40/38/7	82/81/19	118/52	245/119	0.879
Taverna et al.	27/58/16	42/44/13	112/90	128/70	0.783
ApaI	AA/Aa/aa	AA/Aa/aa	A/a	A/a
Zhong et al.	27/54/13	34/60/16	108/80	128/92	0.205
Cyganek et al.	17/39/29	39/100/43	73/97	278/283	0.178

MAF: minor allele frequency.
HWE: Hardy-Weinberg equilibrium.