Statistical Approaches for the Construction and Interpretation of Human Protein-Protein Interaction Network

Algorithm 1

Monte Carlo expectation maximization for parameter estimation.

()     , initialize the parameters

()     while (diff > 0.01)

()       // -Step

()      while ()

()      Sample from

()      Sample from

()      Sample from

()      Sample from

()       

()   

()   calculate function

()   // -Step

()          

()   ;

()   

()   

()   while (1)

()    

()    

()    

()    if (abs() < abs())

()     break

()    

()   

()   diff =

()   

()   

()