Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal

<div>Examples of histograms of flow cytometry data acquisition. The two histograms show results from the acquisition of 5,000 events of a 3% P. falciparum culture after gating on FL1 &gt; 101 (a) and on FL1 &gt; 102 (b). The gating on high FL1 values (&gt;102) selected the mature population of the cultured parasites. The binding of human IgG to IRBC was revealed by an anti-IgG conjugated to thiazole orange (TO). The fluorescence of TO-positive iRBCs was measured in the FL2 channel. The reference negative control (blue curve histogram, Pool NEG), the positive control (green curve, Pool HIS), and a strong responder from Ndiop (red curve, positive sample) are shown. Analysis was done by Flow Jo® Software.</div>

BioMed Research International

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Figure 1

Figure 1: Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal

Figure 1 | Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal 