Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal

Table 2

Levels and prevalence of anti-IgG responses against tested antigens.

Parameters		Cerebral malaria ()	Mild malaria ()	p
IgG anti-PfSchz	(%)	35 (50)	50 (69)	0.021
	ODrt ± SE	3.80 ± 0.29	3.06 ± 0.42	0.063
IgG anti-iRBCm	(%)	35 (50)	63 (88)	0.01
	ODrt ± SE	2.75 ± 0.23	3.87 ± 0.39	0.032
IgG anti-PfEB200	(%)	15 (22)	19 (26)	0.518
	ODrt ± SE	1.38 ± 0.14	1.21 ± 0.36	0.235
IgG anti-R23	(%)	10 (14)	16 (22)	0.236
	ODrt ± SE	2.27 ± 0.33	1.98 ± 0.31	0.452
IgG anti-PfEMP3/5	(%)	37 (54)	30 (42)	0.155
	ODrt ± SE	2.59 ± 0.54	3.82 ± 0.38	0.031

IgG responses in OD ratio ± standard error.
N = number of positive responders that is individuals with OD ratio ≥2, (%) = prevalence of positive responses, ODrt = Mean Optical Densities ratio, SE = standard error, = value resulting from comparison with Mann-Whitney rank or Chi² tests employed, respectively, for ODrt and prevalences of responders.