Metformin Prevents Nonunion after Three-Cannulated-Screw Fixation in Displaced Femoral Neck Fractures: A Retrospective Study

Table 1

Demographic information and characteristics of the fractures.

	Total ()	Union	Nonunion	value
Male	337	290	47	0.077
Female	264	213	51
Age	50.2 ± 5.1	50.2 ± 5.2	49.8 ± 5.1	0.471
BMI	23.1 ± 2.4	23.1 ± 2.4	22.9 ± 2.2	0.428
Garden classification
Stage III	350	298	52	0.257
Stage IV	251	205	46
Pauwel’s classification
Stage I	55	44	11	0.493
Stage II	368	313	55
Stage III	178	146	32
Reduction quality
Anatomical	519	446	73	0.0002
Nonanatomical	82	57	25
T2DM
−	460	380	80	0.193
+	141	123	18
HbA1C
<6%	475	393	82	0.041
6–10%	100	91	9
>10%	26	19	7
Metformin
−	512	420	92	0.008
+	89	83	6
Insulin
−	526	435	91	0.081
+	75	68	7
Alpha-glucosidase inhibitor
−	573	477	96	0.179
+	28	26	2
Secretagogue
−	549	458	91	0.561
+	52	45	7

values are based on the chi-square test. values are based on Student’s -test. values are based on the Fisher exact test.