Biosimilars in Developed and Developing East and Southeast Asian Countries: Japan, South Korea, and Malaysia—Overview, Evolution, and Regulations Assessment

Table 2

Leading biopharmaceuticals sold in Japan, 2015.

Product name	Active agent	Company selling	Company origin
Remicade	Antirheumatic drug	Mitsubishi Tanabe Pharma	J&J
Avastin	Anticancer agent	Chugai Pharmaceutical Co.	Loches
NESP	Renal anemia	Kyowa Hakko Kirin	Kyowa Hakko Kirin
Enbrel	Antirheumatic drug	Takeda	Amgen, Inc.
Herceptin	Anticancer agent	Chugai Pharmaceutical Co.	Loches
Lucentis	Wet age-related macular degeneration	Novartis AG	Roche/Novartis
Rituxan	Anticancer agent	Chugai Pharmaceutical Co.	Roche/Novartis
Humira	Antirheumatic drug	Eisai Co.,  Ltd.	Abbott
Mirusera	Renal anemia	Chugai Pharmaceutical Co.	Chugai Pharmaceutical Co.

Source: Mizuho Bank Industry Research, 2014 [7].