Skeletal Muscle Remodelling as a Function of Disease Progression in Amyotrophic Lateral Sclerosis

Figure 7

Active tissue inflammation to assist in cellular repair. (a and b) Expression levels of CD68 and CD45 mRNA. (c–e) Representative images of tissue macrophages at both BL and 12 wk. time points with a localized distribution in the interstitium between muscle cells. In (a and b) for ALS and for controls. In (c–e) for ALS. Asterisks indicate significant differences from controls; . Scale bar = 50 μm.