Skeletal Muscle Remodelling as a Function of Disease Progression in Amyotrophic Lateral Sclerosis

Table 2

Fibre type distribution in ALS muscle.

	BL	12 wk.
Total fibres (mean)	300.8 ± 83.5	207 ± 38
Type I (%)	52.5 ± 6.3	54.9 ± 9.3
Type II (%)	42.7 ± 15	40.3 ± 7.5
Mixed (%)	4.9 ± 2.0	4.8 ± 1.5
CSA type I (μm^2)	3480 ± 375	3116 ± 763
CSA type II (μm^2)	3998 ± 591	3596 ± 1159
CSA mixed (μm^2)	5807 ± 679	3461 ± 1040

No significant differences are observed for any parameters except for the cross-sectional area (CSA) of mixed fibres, which is reduced at 12 wk. compared to BL ().