Research Article

Evaluation of Influenza Vaccination Efficacy: A Universal Epidemic Model

Table 1

Parameters used for calculations of seasonal influenza outbreak dynamics.

ParameterValueNote

Maximum duration of each stage during disease development (latent, prodromal, and final), days4; 3; 4[30ā€“32]
Day when disease passes from one stage to the other (see (1))3; 2; 2[32, 33]
Mean number of contacts per one infected person5See
Duration of establishing postvaccination immunity, days1See (3)
Rate of infectious activity in final stage, %20See (4)
Rate of infectious activity of immune to nonimmune patients, %50[11]
Rate of infectious activity of cases with mild to severe forms, %10See (5)
Rate of severe forms among nonimmune patients, % 40[34]
Rate of severe forms among immune patients, %20[35]
Rate of sensitivity to infection of immune patients relative to nonimmune ones, %20[25, 26]
Rate of infected contacts per day, %4See (6)
Mortality rate of nonimmune patients in prodromal stage, %0.1See (7)
Mortality rate of immune patients in prodromal stage, %0.03See (7)
Mortality rate of nonimmune patients with severe form in final stage, %0.2See (7)
Mortality rate of immune patients with severe form in final stage, %0.05See (7)
Mortality rate of patients with mild form in final stage, %0.01See (7)
Decrease in mortality rate of treated cases, %30[12]
Duration of contacts observation, days4[30ā€“32]