Relationship between Interdialytic Weight Gain and Blood Pressure in Pediatric Patients on Chronic Hemodialysis

Table 1

Patient (pt) and hemodialysis (HD) characteristics.

Characteristics	Pt 1	Pt 2	Pt 3	Pt 4	Pt 5
Age (years)	17	15	14	17	4
Primary diagnosis	FSGS	Kawasaki disease, MAS	FSGS, failed transplant	Renal dysplasia, failed transplant	FSGS
Race/gender	Black/F	Hispanic/M	Black/F	Black/F	Black/M
HD vintage (months)	39	11	138	7	9
Scheduled antihypertensives	Clonidine Nifedipine	0	0	Labetalol Amlodipine	Lisinopril Amlodipine
Other medications that may contribute to HTN	Norethidrone	Hydrocortisone	Norethidrone	Tacrolimus	—
LVMI percentile (gr/m^2.7) [7]	90	50	90	95–99	95–99
LVM percentile relative to lean body mass [8]	90	50–75	90	75	>97
Urine output	Anephric	Anuric	Anephric	420	800
Mean Kt/V [9]	1.98	2.05	1.80	1.47	1.84
Mean HD duration (min)	233	197	181	185	222
Mean IDWG%	2.93	1.09	2.87	1.79	3.78
Mean EDW (kg)	60.5	38.5	41.2	67.1	21.8

HTN: hypertension; FSGS: focal segmental glomerulosclerosis; MAS: macrophage activation syndrome; HD: hemodialysis; LVMI: left ventricular mass (LVM) index; M: male; F: female; EDW: estimated dry weight (wt); IDWG: interdialytic wt gain (Wt before − Wt after preceding HD); and IDWG%: IDWG expressed as % of EDW [3].
Assessed routinely every 6 months with 24 hr urine collection.
Blood flow rate 170–400 mL/min, dialysate flow rate 600 mL/min, and dialysate Na 138 mEq/L.