Table 1: Effects of VPA on renal function and urinary biochemistry.

SHAM
()
IRI
()
IRI + VPA
()

BUN (mg/dL)13 ± 1145 ± 3539 ± 11
Creatinine (mg/dL)0.2 ± 0.02.7 ± 0.40.5 ± 0.1
FENa (%)0.2 ± 0.14.9 ± 10.5 ± 0.1
FEK (%)22 ± 3129 ± 1717 ± 1.4
Urinary protein/creatinine1.85 ± 0.23.9 ± 0.82.18 ± 0.2

BUN: blood urea nitrogen; FENa: fractional excretion of sodium; FEK: fraction excretion of potassium; IRI: ischemia-reperfusion injury; VPA: valproic acid.
Results are expressed as mean ± SEM. versus SHAM and IRI + VPA.