Review Article
The Effect of Teriparatide on Fracture Healing of Osteoporotic Patients: A Meta-Analysis of Randomized Controlled Trials
Table 5
The GRADE evidence quality for each outcome.
| | Interventions for condition in population |
| | Outcomes intervention and comparison intervention | Illustrative comparative risks (95% CI) | Relative effect (95% CI) | Number of participants (studies) | Quality of the evidence (GRADE) | Comments | Assumed risk
With comparator | Corresponding risk
With intervention |
| | Fracture healing time | | | | | | | | Teriparatide/fracture healing | The mean fracture healing time in the control groups was
9.1–23 weeks | The mean fracture healing time in the intervention groups was
4.54 lower
(8.8 to 0.28 lower) | | 157
(3 studies) | ⊕⊕⊖⊖
low | |
| | Functional outcome | | | | | | | | Teriparatide/fracture healing | The mean functional outcome in the control groups was
25.8–56.3 points | The mean functional outcome in the intervention groups was
1.02 standard deviations lower
(1.81 to 0.22 lower) | | 225
(4 studies) | ⊕⊕⊖⊖
low | |
|
|
