Research Article

Kinetics of Cardiac Output at the Onset of Exercise in Precapillary Pulmonary Hypertension

Table 3

Parameters describing the heart rate (HR), stroke volume (SV), and cardiac output (CO) kinetics upon exercise onset for PH patients () and control subjects (). , baseline mean value as determined by model 1; min, minimal value detected by models 2 and 3; , amplitude of the parameter increase; , time constant; , time delay of the exponential; , time of minimal value determined for models 2 and 3; MRT, mean response time; ss, steady-state exercise mean value as determined by the model. Analysis with model 2 was possible only for 8 control subjects.

PH ()
or min (s) or (s)MRT (s)ss

HR (min−1)Model 1
Model 2
Model 3

SV (ml)Model 1
Model 2
Model 3

CO (l⋅min−1)Model 1
Model 2
Model 3

Controls ()
or min (s) or (s)MRT (s)ss

HR (min−1)Model 1
Model 2
Model 3

SV (ml)Model 1
Model 2
Model 3

CO (l⋅min−1)Model 1
Model 2
Model 3