MP Resulting in Autophagic Cell Death of Microglia through Zinc Changes against Spinal Cord Injury

Figure 1

MP promoted neurologic motor function and histologic assessment in SCI rat. (a) BBB scores of rats in SCI-only group and MP group at each time point (3 d, 7 d, 21 d, and 60 d) after injury. Data were expressed as mean ± SD ( for each group); (b) representative sections of spinal cords in the ventral horn of gray matter stained with cresyl violet at 72 h after injury. Normal neurons exhibited a fine cytoplasm with Nissl substance (arrows); scale bar = 100 μm; (c) quantitative motor neurons counts in the ventral gray matter at 72 h after injury. Data were expressed as mean ± SEM ( for each group). versus normal group; versus SCI group.

(a)

(b)

(c)