Research Article

Aqueous Leaf Extract of Jatropha mollissima (Pohl) Bail Decreases Local Effects Induced by Bothropic Venom

Table 2

Maximum percentage of inhibition of J. mollissima against local effects produced by Bothrops erythromelas and B. jararaca venoms. Percentage of inhibition was calculated as [1 – (% activity of test mean – % activity of PBS control mean)/(% activity of Ber or Bja control mean – % activity of PBS control mean)] × 100.

ActivityDoseInhibition (%)

Bothrops erythromelasEdematogenic50 mg/kg46.41
Inflammatory100 mg/kg81.81
Myotoxic200 mg/kg81.70

Bothrops jararacaHemorrhagic200 mg/kg44.00
Edematogenic200 mg/kg25.19
Inflammatory200 mg/kg80.18
Myotoxic100 mg/kg72.73

edematogenic activity was calculated using the area under the curve.