Research Article

Effect of Prophylactic Antifungal Protocols on the Prognosis of Liver Transplantation: A Propensity Score Matching and Multistate Model Approach

Table 4

Results of multivariable transition-specific Cox models.

VariableCategoryHR (95% CI) value

Transition: transplant to fungal infection
TreatmentNo prophylaxis1
Prophylaxis0.57 (0.34–0.96)0.033
AscitesMild/moderate1
Massive1.65 (0.98–2.76)0.058
Propensity score0.15 (0.01–1.76)0.132

Transition: transplant to death
AscitesMild/moderate1
Massive1.55 (1.02–2.36)0.042
Living donor
(within 1.5 years)
No1
Yes0.41 (0.26–0.66)<0.001
Living donor
(after 1.5 years)
No1
Yes1.08 (0.45–2.62)0.861

Transition: fungal infection to death
Age (years)≤501
>50, ≤602.55 (1.10–5.93)0.029
>601.80 (0.67–4.83)0.240
AscitesMild/moderate1
Massive2.19 (1.06–4.52)0.035
Living donorNo1
Yes0.57 (0.28–1.14)0.113

HR: hazard ratio and CI: confidence interval. .