Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1<i>β</i>-Induced Inflammation and Apoptosis in Chondrocytes

<div>Western blot analysis of Bcl-2, Bax, and caspase-3. Lanes: 1, blank; 2, control; 3, CS; 4, HA-CS; 5, CS-IL-1Ra; 6, HA-CS-IL-1Ra. Protein levels were normalized to <i>β</i>-actin. Values were expressed as the mean ± standard deviation. IL-1Ra: interleukin-1 receptor antagonist; HA: hyaluronic acid; CS: chitosan; Bcl-2: B-cell lymphoma 2; Bax: Bcl-2-associated X protein.</div>

BioMed Research International

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Figure 7

Figure 7: Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1<i>β</i>-Induced Inflammation and Apoptosis in Chondrocytes 

Figure 7 | Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1β-Induced Inflammation and Apoptosis in Chondrocytes 