Research Article

Perinatal and Neonatal Outcomes of Patients Who Were Diagnosed with Neural Tube Defect in Midtrimester Fetal Ultrasound Scan and Refused Request for Termination of Pregnancy

Table 1

Baseline maternal and pregnancy characteristics of patients diagnosed NTD in midtrimester fetal ultrasound scan.


Age (year)
 Younger than 2510 (14.5)
 25–34.946 (66.7)
 35 or older13 (18.8)
Number of prior pregnancies 20 weeks of gestation or greater
 0 (nulliparous) 3 (4.3)
 118 (26.1)
 216 (23.2)
 3 or more32 (46.4)
History of fetus having NTD in previous pregnancies 1 (1.4)
Periconceptional folic acid use55 (79.8)
Consanguinity between spouses13 (18.8)
Gestational age at diagnosis20 (15–24)
Reason for admission
 Routine obstetric visit2 (2.8)
 Elevation in maternal AFP MoM levels4 (5.6)
 Referred due to abnormal USG finding63 (91.6)
The level of neural tube defect
 Cervical3 (4.3)
 Thoracal1 (1.4)
 Thoracolumbar9 (13.0)
 Lumbar24 (34.8)
 Lumbosacral28 (40.7)
 Sacral4 (5.8)
Detection of lemon sign in USG62 (89.8)
Detection of banana sign in USG59 (85.5)
Detection of ventriculomegaly in USG64 (92.7)
Detection of pes equinovarus deformity in USG15 (21.7)
Associated anomaly (excluding clubfoot and Chiari II findings)3 (4.3)

Data are given as (%).
Data are given as median [interquartile range].