Research Article

Acute Aortic Dissection Biomarkers Identified Using Isobaric Tags for Relative and Absolute Quantitation

Table 3

Subset of differentially expressed proteins between the AAD and control groups.

AccessionNameBiological processProtein classAAD : CONUpregulated/downregulated

1P02748Complement component C9Response to stimulusReceptor1.9231Up
2P51884LumicanCell-cell adhesionReceptor1.4191Up
3P00450CeruloplasminBlood coagulationTransporter1.9055Up
4P00751Complement factor BBlood coagulationTransfer/carrier protein1.3932Up
5P02741CRPResponse to stressDefense/immunity protein7.379Up
6P00738HaptoglobinBlood coagulationProtease0.2535Down
7P02649Apolipoprotein ELipid metabolic processTransporter0.3565Down
8P04114Apolipoprotein B-100Lipid metabolic processTransfer/carrier protein0.3767Down
9P07996TSP-1Blood coagulationTransfer/carrier protein0.4699Down
10P01019AngiotensinogenProtein metabolic processEnzyme modulator0.5395Down

This table lists the five highest Unused ProtScores from the upregulated proteins and downregulated proteins. AAD, acute aortic dissection. CON, normal controls.