Acute Aortic Dissection Biomarkers Identified Using Isobaric Tags for Relative and Absolute Quantitation

Table 4

Comparison of Lumican, CRP, TSP-1, and D-dimer serum concentrations (mean ± SD).

	AAD group	Non-AAD group	Normal controls
Lumican (ng/mL)	3.39 ± 1.66	1.12 ± 0.56	0.42 ± 0.31
CRP (mg/L)	35.17 ± 38.61	19.01 ± 25.17	5.13 ± 2.06
TSP-1 (ng/mL)	6052.99 ± 1657.3	6995.38 ± 8053.64	798.49 ± 930.6
D-dimer (mg/L)	13.48 ± 20.75	1.62 ± 2.62	0.12 ± 0.06

Compared with the non-AAD group, serum levels of Lumican, CRP, and D-dimer were significantly higher in the AAD group (), while serum levels of TSP-1 were not significantly different (). Compared with the control group, the serum levels of Lumican, CRP, TSP-1, and D-dimer were significantly higher in the AAD group ().