In Vitro Cytokine Expression and In Vivo Healing and Inflammatory Response to a Collagen-Coated Synthetic Bone Filler

Figure 5

Microscopic evaluation after 26 weeks. (a) The majority of the granules (SB) are surrounded by trabecular bone in the bone marrow (2x objective); (b) granule of SB in the periosteum is surrounded by macrophages and there is a minimal thickening of the fibrous periosteum (20x objective); (c) the tissue response is prominent in the periosteum and cortical region of the implant (BS) (2x objective); (d) inflammatory cells and fibrosis surrounding the implant (BS) in the cortical area of the implant (20x objective).