Epidemiology of American Tegumentary Leishmaniasis and Trypanosoma cruzi Infection in the Northwestern Argentina

Figure 2

Flow chart showing the groups of patients and noninfected people included in prevalence (LP) and case-control study of leishmaniasis and T. cruzi seroprevalence (TCSP) infection. Mixed infections detected (T. cruzi-Leishmania) from 13 patients with active leishmaniasis ulcer in 2009 are also shown. Diagnostic of T. cruzi infection applied to the 100 people to detect both seropositive people to calculate T. cruzi seroprevalence and select the negative control people for the case-control study. People positive for ELISA-leishmaniasis or leishmanin skin test (LST) may have been exposed to the Leishmania parasite. The cross-reaction of both ELISA and leishmanin skin test with chagasic infection does not distinguish whether the person was exposed to Leishmania parasite or is infected with T. cruzi. Due to this, the people positive for Chagas lab tests were not included as controls in the case-control study.