Prognostic Factors and Clinical Characteristics of Patients with Primary Duodenal Adenocarcinoma: A Single-Center Experience from China

Table 2

Results of the Cox regression to identify independent potential variables influencing overall survival of patients undergoing resection for duodenal adenocarcinoma.

Characteristics	Univariable analysis		Multivariable analysis
	Hazard ratio	value	Hazard ratio	value
	1.53 (0.92–2.54)	0.100
Gender (male versus female)	1.56 (0.94–2.58)	0.087
	0.80 (0.55–1.67)	0.246
Tumor	0.56 (0.29–1.11)	0.098
Tumor	0.84 (0.43–1.61)	0.589
T	1.84 (1.35–2.52)	<0.001	1.05 0.58–1.92	0.866
	0.79 (0.66–0.95)	0.013	0.84 0.65–1.10	0.210
Vascular invasion (yes versus no)	3.71 (1.94–7.08)	<0.001	3.75 1.24–11.39	0.020
Perineurial invasion (yes versus no)	2.19 (1.05–4.55)	0.036	0.49 0.16–1.49	0.211
Lymph node metastasis (yes versus no)	5.77 (3.32–10.02)	<0.001	31.76 2.14–470.8	0.012
TNM	1.94 (1.49–2.52)	<0.001	0.51 0.18–1.45	0.207
CEA level (elevated versus normal)	2.09 (1.07–4.09)	0.032	1.26 0.41–3.88	0.689
Transfusion (yesversus no)	1.16 (0.70–1.93)	0.560
Recurrence and metastasis (yes versus no)	4.66 (2.73–7.96)	<0.001	1.67 0.65–4.28	0.281
Adjuvant therapy (yes versus no)	1.25 (0.75–2.09)	0.389

as continuous variable.