Table 3: Genotypes and allele frequencies distribution of gene polymorphisms between two patient groups and control subjects.

Genotype and allele frequencyEHTEHT+T2DMControl
(%) (%) (%)

Insertion/deletion
II57 (76)71 (80.7)133 (84.7)
ID12 (16)14 (15.9)21 (13.4)
DD6 (8)3 (3.4)3 (1.9)
I126 (84)156 (88.6)287 (91.4)
D12 (16)20 (11.4)27 (8.6)
value 0.027/0.0150.219/0.200
Post hoc test
II vs ID0.749
II vs DD0.056
ID vs DD0.195
Odds ratio (95% CI)0.494 (0.274–0.890)0.734 (0.399–0.890)
A191G
GG54 (72)69 (78.4)124 (79)
GA17 (22.7)17 (19.3)31 (19.7)
AA4 (5.3)2 (2.3)2 (1.3)
G125 (83.3)155 (89.1)279 (88.9)
A25 (16.7)19 (10.9)35 (11.1)
value0.761/0.0670.451/0.534
Odds ratio (95% CI)0.627 (0.360–1.093)1.023 (0.566–1.850)

EHT refers to essential hypertensive patients, EHT + T2DM refers to essential hypertensive patients with Type 2 Diabetes Mellitus, and control refers to healthy subjects. value < 0.05.