Research Article

Genetic Analysis of the Atrial Natriuretic Peptide Gene Polymorphisms among Essential Hypertensive Patients in Malaysia

Table 4

Genotype analysis based on race.

RaceEHTEHT + T2DMControl
IIIDDDIIIDDDIIIDDD

Malay20 (69.0)7 (24.1)2 (6.9)27 (79.4)6 (17.6)1 (2.9)52 (78.8)13 (19.7)1 (1.5)
Chinese27 (93.1)0 (0.0)2 (6.9)20 (90.9)1 (4.5)1 (4.5)54 (93.1)3 (5.2)1 (1.7)
Indian10 (58.8)5 (29.4)2 (11.8)24 (75.0)7 (21.9)1 (3.1)27 (81.8)5 (15.2)1 (3.0)
value0.0330.5700.189

GGGAAAGGGAAAGGGAAA

Malay19 (65.5)9 (31.0)1 (3.4)25 (73.5)8 (23.5)1 (2.9)46 (69.7)20 (30.3)0 (0.0)
Chinese26 (89.7)2 (6.9)1 (3.4)20 (90.9)1 (4.5)1 (4.5)52 (89.7)5 (8.6)1 (1.7)
Indian9 (52.9)6 (35.3)2 (11.8)24 (75.0)8 (25.0)0 (0.0)26 (78.8)6 (18.2)1 (3.0)
value0.0460.2640.021

EHT refers to essential hypertensive patients, EHT + T2DM refers to essential hypertensive patients with Type 2 Diabetes Mellitus, and control refers to healthy subjects. value < 0.05.