Genetic Analysis of the Atrial Natriuretic Peptide Gene Polymorphisms among Essential Hypertensive Patients in Malaysia
Table 5
Allele frequency analysis based on gender.
Alleles of gene polymorphisms
EHT
EHT + T2DM
Control
Male
Female
Male
Female
Male
Female
Insertion/deletion
I
77
49
76
80
132
155
D
17
7
10
10
16
11
value
0.456
0.551
0.228
Odds ratio
0.647 (0.250–1.674)
0.950 (0.374–2.410)
0.585 (0.263–1.306)
A191G
G
77
48
75
80
128
151
A
17
8
11
10
20
15
value
0.653
0.818
0.215
Odds ratio
0.755 (0.303–1.884)
852 (0.342–2.123)
0.636 (0.313–1.293)
EHT refers to essential hypertensive patients, EHT + T2DM refers to essential hypertensive patients with Type 2 Diabetes Mellitus, and control refers to healthy subjects. value > 0.05.
