Efficacy Comparison of Tenofovir and Entecavir in HBeAg-Positive Chronic Hepatitis B Patients with High HBV DNA

Table 3

Cox regression analysis identifying independent variables predictive of virological response.

Variables	HR (95% CI)
Gender	0.522 (0.273–0.997)	0.07
Age	1.005 (0.966–1.045)	0.81
Height	1.018 (0.974–1.063)	0.43
Weight	0.994 (0.965–1.024)	0.68
Alcohol history	1.158 (0.677–1.983)	0.59
Smoking history	0.967 (0.558–1.675)	0.90
Family history	1.739 (1.083–2.794)	0.07
ALT baseline (U/L)	1.000 (0.998–1.002)	0.84
HBV DNA baseline ( IU/mL)	0.904 (0.699–1.169)	0.44
Therapy with TDF versus ETV	0.896 (0.552–1.457)	0.66

TDF, tenofovir; ETV, entecavir; ALT, alanine aminotransferase; IU/mL, international unit per milliliter; U/L, unit per liter; HR, hazard ratio; CI, confidence interval.