Cornel Iridoid Glycoside Improves Locomotor Impairment and Decreases Spinal Cord Damage in Rats

Figure 3

Effects of CIG on volume of lesion epicenter and spared tissue in injured spinal cord. Myelin basic protein (MBP) immunostaining with cresyl violet counterstaining was used to measure the stereological parameters of spinal cord lesion. (a) The representative coronary section of injured spinal cord in different groups. (b) The enlarged images of white and grey matter in normal and injured spinal cord. (c) The quantitative analyses for the volume of different parts of the spinal cord samples from actual stereological measurements. LEp, lesion epicenter; GM, grey matter; WM, white matter. (d) The ratio of the volume of different parts (, , and ) to the total segment volume (). Data are expressed as mean ± SEM from 3 rats in each group. , , the SCI model group versus the sham control group; , , CIG-treated groups versus the model group.

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