Evolution of bopA Gene in Burkholderia: A Case of Convergent Evolution as a Mechanism for Bacterial Autophagy Evasion

Figure 3

The consensus sequence logo for the LIR motif. The three logos are based on different LIR motifs distributed in the protein BopA of Burkholderia (a), the protein IcsB of Shigella, and 21 different p62 proteins that all bind directly to ATG8 family proteins in human (c). The pattern of LIR motif is D/S/E/TX F/W/YXXI/L/V.

(a)

(b)

(c)