One-Piece Zirconia Ceramic versus Titanium Implants in the Jaw and Femur of a Sheep Model: A Pilot Study

Figure 5

Histology images of sheep jaw stained with MacNeal’s tetrachrome at 12 weeks of healing. (a) Titanium implant at 2x. (b) Titanium implant at 4x. (c) Zirconia implant at 2x. (d) Zirconia implant at 4x. Old mineralized bone (OB). New bone (NB), unmineralized bone. Arrows represent the lining of osteoblast cells with osteogenic potential. Immediately following the deposition of osteoid, multinucleated osteoblasts commence the remodelling process and the formation of a Haversian system. Osteoid undergoes maturational changes that prepare them for the initial deposition of calcium phosphate crystals called mineralization front. Osteons (red asterisks) represent the structural end result of a focus of bone remodelling. Black asterisks represent hematopoietic and fatty marrow. Haversian canals (HC) enclose vascular structures, nerves, and lining cells. The development of primary and secondary osteons representing active bone formation and high BIC is visible in the figure. Scale bar: 100 μm.

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