Effect of Low-Pressurized Perfusion with Different Concentration of Elastase on the Aneurysm Formation Rate in the Abdominal Aortic Aneurysm Model in Rabbits

Figure 3

Histomorphometric changes in groups A to E (a). HE: hematoxylin and eosin stain (400); EVG: elastic Van Gieson stain (400), MASSON: Masson’s stain (400). CD68: CD68 macrophages staining (400). As shown by CD68 staining, the number of CD68 positive cells infiltrating the aortic wall increased from group A to group E. Compared with group A, the number of CD68 positive cells in group D and group E increased significantly, ; the difference was statistically significant (b). EVG stain shows that the elastic fibrous tissue wavy in group A is clear, while that in group E is in disorder and fuzzy. Compared with group A, the destruction amount of elastic fiber in group D and group E obviously increased, ; the difference was statistically significant (c). Masson’s stain shows that the collagen fiber content increased gradually from group A and group E. Compared with group A, the collagen fiber content in group D and group E increased significantly, ; the difference was statistically significant (d).

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