A Five-Gene Expression Signature Predicts Clinical Outcome of Ovarian Serous Cystadenocarcinoma

Table 4

Cox proportional hazard regression analyses in training and testing sets.

Variables	Univariable model		Multivariable model
	HR (95% CI)	value	HR (95% CI)	value
Training group
Five-gene model	2.672 (1.801–3.965)	<0.001	2.536 (1.832–3.509)	<0.001
Age	1.683 (1.153–5.457)	0.007	1.013 (0.994–1.031)	0.173
Testing group
Five-gene model	2.248 (1.397–3.620)	0.001	2.224 (1.379–3.586)	0.001
Age	1.224 (0.772–1.941)	0.389	1.153 (0.726–1.830)	0.546
Training group
Five-gene model	2.672 (1.801–3.965)	<0.001	2.725 (1.821–4.078)	<0.001
Stage	1.080 (0.670–1.741)	0.752	0.883 (0.541–1.442)	0.62
Testing group
Five-gene model	2.248 (1.397–3.620)	0.001	2.385 (1.387–3.562)	<0.001
Stage	1.032 (0.580–1.461)	0.453	0.685 (0.432–1.238)	0.428