Research Article

Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Isolates Causing Invasive and Noninvasive Pneumococcal Diseases in Korea from 2008 to 2014

Table 4

Resistance rates to antimicrobial agents by age.

AntibioticTotal (378)⁢≤5 years ()⁢≥65 years ()⁢6–64 years ()
IRSIRSIRSIRS

Amoxicillin30 (8.2) 61 (16.8)273 (75.0)3 6 718 37138 9 18128
Azithromycin11 (3.2)244 (72.0) 84 (24.8)13 2 7126 39 4105 43
Cefaclor12 (3.7)222 (68.7) 89 (27.6)12 3 7115 45 5 95 41
Cefepime73 (22.0) 22 (6.6)237 (71.4)4 4 836 1212333 6106
Cefotaxime30 (9.4) 13 (4.1)277 (86.6)6 2 713 814311 3127
Ceftriaxone33 (10.2) 15 (4.7)274 (85.1)6 3 613 1014214 2126
Cefuroxime IV11 (3.7)199 (66.1) 91 (30.2)12 2 8101 46 3 86 43
Chloramphenicol 3 (0.9) 91 (26.7)247 (72.4) 114 3 50120 40113
Clindamycin193 (56.9)146 (43.1)13 2106 71 74 73
Erythromycin 5 (1.4)258 (73.3) 89 (25.3)13 2 4135 42 1110 45
Levofloxacin 2 (0.6) 26 (7.2)331 (92.2)16 2 19164 7151
Meropenem114 (32.9) 91 (26.2)142 (40.9)7 6 353 50 7454 35 65
Penicillin IV57 (17.8) 29 (9.0)235 (73.2)7 3 528 1412222 12108
Tetracycline 5 (1.4)256 (72.7) 91 (25.9)13 2 2130 49 3113 40
Trimethoprim/sulfa38 (10.3)141 (38.3)189 (51.4)111 417 78 9620 52 89
Vancomycin  352 (100)  15  181  156

I: intermediate; R: resistant; S: susceptible.