Table 3: Cytokines values before the first extracorporeal granulocyte therapy, after the second extracorporeal granulocyte therapy, and after 7 days (median/0.25–0.75 quartile).

CytokineBefore first extracorporeal therapy (day 1) (, pg/mL)After second extracorporeal therapy (day 3) (, pg/mL)After 7 days (day 8) (, pg/mL)

IL-657 (41–159)78 (45–154)28 (26–62)
IL-840 (28–53)57 (38–118)30 (29–36)
TNF-alpha30 (22–40)22 (19–26)15 (13–17)
IL-1015 (8–20)11 (8–13)3 (3–8)

Statistically significant () compared to day 1 (before first extracorporeal treatment).
Statistically significant () compared to the end of second extracorporeal treatment.
IL: interleukin.
TNF: tumor necrosis factor.