Bioartificial Therapy of Sepsis: Changes of Norepinephrine-Dosage in Patients and Influence on Dynamic and Cell Based Liver Tests during Extracorporeal Treatments

Table 3

Cytokines values before the first extracorporeal granulocyte therapy, after the second extracorporeal granulocyte therapy, and after 7 days (median/0.25–0.75 quartile).

Cytokine	Before first extracorporeal therapy (day 1) (, pg/mL)	After second extracorporeal therapy (day 3) (, pg/mL)	After 7 days (day 8) (, pg/mL)
IL-6	57 (41–159)	78 (45–154)	28 (26–62)
IL-8	40 (28–53)	57 (38–118)	30 (29–36)
TNF-alpha	30 (22–40)	22 (19–26)	15 (13–17)
IL-10	15 (8–20)	11 (8–13)	3 (3–8)

Statistically significant () compared to day 1 (before first extracorporeal treatment).
Statistically significant () compared to the end of second extracorporeal treatment.
IL: interleukin.
TNF: tumor necrosis factor.