Influence of Botulinumtoxin A on the Expression of Adult MyHC Isoforms in the Masticatory Muscles in Dystrophin-Deficient Mice (Mdx-Mice)

Figure 2

Western blot analysis of fast and slow skeletal muscle myosin extracted from 100-day-old mice (control/mdx) 21 days after BTX-A injection into the right masseter muscle. (a) Representative blots, (b) quantitative analyses of slow myosin (MyHC-I), and (c) fast myosin (MyHC-II) compared to GAPDH in masticatory muscle of BTX-A treated control- (C57Bl) and mdx-mice. Mean optical density (MOD) ± SEM are given in all cases for muscle samples of different animals and three-independent Western blot analysis (Student’s t-test; treated versus untreated masseter muscle).

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