Research Article

A Modified Carbon Monoxide Breath Test for Measuring Erythrocyte Lifespan in Small Animals

Table 1

Physiological parameters of the groups on day 20 of ribavirin treatment.

GroupWeight (kg)Blood volume (mL)Hemoglobin (g/L)Reticulocyte (%)Bilirubin (μmol/L)CO (ppm)
TotalIndirect

CON52.7 ± 0.2186 ± 54117 ± 1.12.1 ± 0.40.8 ± 0.090.3 ± 0.110.81 ± 0.19
RIB1052.7 ± 0.3130 ± 17117 ± 5.76.5 ± 0.81.5 ± 0.280.8 ± 0.130.92 ± 0.18
RIB2052.8 ± 0.2128 ± 14107 ± 6.611.7 ± 1.81.7 ± 0.111.1 ± 0.091.00 ± 0.05

, versus CON. , versus RIB10.