Effect of Diabetes Mellitus on Tuberculosis Treatment Outcome and Adverse Reactions in Patients Receiving Directly Observed Treatment Strategy in India: A Prospective Study
Table 4
Association of treatment outcomes and different variables in TB patients.
Variables
Poor outcome ()
Treatment success ()
value
Sex
0.32
Male
15 (65.2)
160 (54.6)
Female
08 (34.8)
133 (45.4)
Category
<0.001
Category I
12 (52.2)
243 (82.9)
Category II
11 (47.8)
50 (17.1)
TB types
<0.001
PTB
23 (100)
168 (57.3)
EPTB
00
125 (42.7)
Family history of TB
0.94
Yes
03 (13.1)
40 (13.6)
No
20 (86.9)
253 (86.3)
Alcoholic history
0.08
Yes
12 (52.2)
100 (34.1)
No
11 (47.8)
193 (65.9)
Smoking history
0.04
Yes
09 (39.1)
62 (21.2)
No
14 (60.8)
231 (78.8)
Chewing history
0.51
Yes
05 (21.7)
48 (16.4)
No
18 (78.2)
245 (83.6)
ADR
0.74
Present
17 (73.9)
207 (70.6)
Absent
06 (26.1)
86 (29.3)
Cough
0.25
Present
20 (86.9)
224 (76.4)
Absent
03 (13.1)
69 (23.5)
Weight loss
0.02
Present
18 (78.3)
270 (92.1)
Absent
05 (21.7)
23 (7.8)
Anorexia
0.09
Present
19 (82.6)
192 (65.5)
Absent
04 (17.4)
101 (34.5)
Fever
0.008
Present
20 (86.9)
173 (59.1)
Absent
03 (13.0)
120 (40.9)
Dyspnea
0.01
Present
18 (78.3)
151 (51.5)
Absent
05 (21.7)
142 (48.4)
Chest pain
0.04
Present
17 (73.9)
150 (51.2)
Absent
06 (26.1)
143 (48.8)
Hemoptysis
0.13
Present
12 (52.2)
106 (36.2)
Absent
11 (47.8)
187 (63.8)
DM
0.42
Present
05 (21.7)
45 (15.4)
Absent
18 (78.3)
248 (84.6)
Poor outcome: default, death, failure, and regimen changed; treatment success: cured and treatment completed; PTB: pulmonary tuberculosis; EPTB: extrapulmonary tuberculosis; DM: diabetes mellitus; ADR: adverse drug reaction; data was analyzed using chi square test. was considered as significant. , , and .
