Effect of Diabetes Mellitus on Tuberculosis Treatment Outcome and Adverse Reactions in Patients Receiving Directly Observed Treatment Strategy in India: A Prospective Study
Table 5
Association of clinical manifestations with sputum positivity and treatment outcomes among TB patients by multivariate analyses.
Variables
Sputum positive > 60 days OR (95% CI)
Poor outcome OR (95% CI)
DM
0.633 (0.206–1.949)
0.714 (0.155–3.279)
Men
1.284 (0.327–4.430)
0.312 (0.055–1.762)
Age
0.992 (0.957–1.029)
0.960 (0.904–1.020)
Category
1.685 (0.647–4.391)
0.838 (0.243–2.888)
BMI
0.914 (0.794–1.052)
1.185 (0.970–1.447)
TB history
1.797 (0.491–6.582)
2.591 (0.260–25.821)
Alcohol intake
0.880 (0.280–2.764)
0.674 (0.177–2.558)
Smoking
1.811 (0.673–4.877)
0.752 (0.236–2.390)
Chewing
0.689 (0.252–1.883)
0.778 (0.241–2.543)
ADR incidence
1.797 (0.491–6.582)
0.642 (0.187–2.207)
Weight gain
0.914 (0.141–5.915)
0.708 (0.059–8.521)
Anorexia
1.165 (0.060–22.585)
0.558 (0.048–3.124)
Fever
2.176 (0.321–14.734)
0.814 (0.093–2.155)
Dyspnea
0.138 (0.010–1.902)
1.973 (0.337–5.871)
Chest pain
0.090 (0.010–0.847)
1.370 (0.485–6.143)
Hemoptysis
1.582 (0.062–0.551)
0.813 (0.291–2.275)
OR: odds ratio; CI: confidence interval; BMI: body mass index; ADR: adverse drug reaction; DM: diabetes mellitus. All independent variables were analyzed using multiple logistic regression analysis to calculate the odds ratio. The OR presented is adjusted for age, gender, and BMI in logistic regression analysis. was considered as significant.
