Research Article

The Effect of Altitude on Intraocular Pressure in Vitrectomized Eyes with Sulfur Hexafluoride Tamponade by the Friedenwald Method: Rabbit Animal Model

Table 4

Regression lines and slopes per case and per scleral rigidity coefficient (estimates for human eyes).

CaseRegressionIOP increase/100 m altitude rise mmHg (95% CI)Significance (95% CI) Benchmark: 100% SF6

Friedenwald
100% SF62.1 (1.7 to 2.5)
50% SF61.8 (0.6 to 3.0)NS
100% Air1.4 (0.3 to 2.5)NS
25% SF61.1 (0.2 to 2.0)NS
Pneum0.4 (−0.4 to 1.3)Sig
BSS0.1 (−0.6 to 0.9)Sig

Dastiridou mean
100% SF62.2 (1.8 to 2.6)
50% SF61.9 (0.7 to 3.1)NS
100% Air1.5 (0.3 to 2.6)NS
25% SF61.2 (0.2 to 2.1)NS
Pneum0.4 (−0.5 to 1.3)Sig
BSS0.1 (−0.6 to 0.9)Sig

Pallikaris
100% SF61.0 (0.7 to 1.3)
50% SF60.9 (0.3 to 1.5)NS
100% Air0.7 (0.1 to 1.3)NS
25% SF60.6 (0.1 to 1.1)NS
Pneum0.2 (−0.3 to 0.7)Sig
BSS0.1 (−0.4 to 0.5)Sig

Dastiridou max
100% SF64.4 (4.0 to 4.8)
50% SF63.8 (1.4 to 6.1)NS
100% Air2.8 (0.9 to 4.8)NS
25% SF62.1 (0.5 to 3.7)Sig
Pneum0.7 (−0.7 to 2.1)Sig
BSS0.2 (−0.9 to 1.3)Sig

Linear regression estimation for human eyes. IOP: intraocular pressure. SF6: sulfur hexafluoride. BSS: balanced saline solution. Pneum: rabbit eye without vitrectomy and 100% SF6. NS: not significant. Sig: significant.