Table of Contents Author Guidelines Submit a Manuscript
Table of Contents Alerts

To receive news and publication updates for BioMed Research International, enter your email address in the box below.

BioMed Research International
Volume 2016, Article ID 7367485, 11 pages
http://dx.doi.org/10.1155/2016/7367485
Review Article

Circulating Resistin Levels and Risk of Colorectal Cancer: A Meta-Analysis

Gui Yang,1 Wei Fan,2 Baohong Luo,2 Zhigao Xu,3 Ping Wang,2 Shihui Tang,2 Peipei Xu,2 and Mingxia Yu1,2

1Department of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
2Department of Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
3Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

Received 10 May 2016; Accepted 20 July 2016

Academic Editor: Oreste Gualillo

Copyright © 2016 Gui Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Siegel, C. Desantis, and A. Jemal, “Colorectal cancer statistics, 2014,” CA: A Cancer Journal for Clinicians, vol. 64, no. 2, pp. 104–117, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Baena and P. Salinas, “Diet and colorectal cancer,” Maturitas, vol. 80, no. 3, pp. 258–264, 2015. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Ma, Y. Yang, F. Wang et al., “Obesity and risk of colorectal cancer: A Systematic Review of Prospective Studies,” PLoS ONE, vol. 8, no. 1, article e53916, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. S.-Y. Na and S.-J. Myung, “Obesity and colorectal cancer,” Taehan Sohwagi Hakhoe Chi, vol. 59, no. 1, pp. 16–26, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. G. De Pergola and F. Silvestris, “Obesity as a major risk factor for cancer,” Journal of Obesity, vol. 2013, Article ID 291546, 11 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. C. R. Guffey, D. Fan, U. P. Singh, and E. A. Murphy, “Linking obesity to colorectal cancer: recent insights into plausible biological mechanisms,” Current Opinion in Clinical Nutrition and Metabolic Care, vol. 16, no. 5, pp. 595–600, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Vazzana, S. Riondino, V. Toto et al., “Obesity-driven inflammation and colorectal cancer,” Current Medicinal Chemistry, vol. 19, no. 34, pp. 5837–5853, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Yehuda-Shnaidman and B. Schwartz, “Mechanisms linking obesity, inflammation and altered metabolism to colon carcinogenesis,” Obesity Reviews, vol. 13, no. 12, pp. 1083–1095, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Jiang, D. W. Park, J.-M. Tadie et al., “Human resistin promotes neutrophil proinflammatory activation and neutrophil extracellular trap formation and increases severity of acute lung injury,” Journal of Immunology, vol. 192, no. 10, pp. 4795–4803, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. D. S. Popovic, D. Tomic-Naglic, and E. Stokic, “Relation of resistin, leptin and adiponectin—trinity of adipose tissue dysfunction assessment,” European Journal of Internal Medicine, vol. 25, no. 6, pp. e80–e81, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. C. M. Steppan, E. J. Brown, C. M. Wright et al., “A family of tissue-specific resistin-like molecules,” Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 2, pp. 502–506, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. J. C. Engert, M.-C. Vohl, S. M. Williams et al., “5′ Flanking variants of resistin are associated with obesity,” Diabetes, vol. 51, no. 5, pp. 1629–1634, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. S. D. Patel, M. W. Rajala, L. Rossetti, P. E. Scherer, and L. Shapiro, “Disulfide-dependent multimeric assembly of resistin family hormones,” Science, vol. 304, no. 5674, pp. 1154–1158, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. I. N. Holcomb, R. C. Kabakoff, B. Chan et al., “FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family,” The EMBO Journal, vol. 19, no. 15, pp. 4046–4055, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Codoñer-Franch and E. Alonso-Iglesias, “Resistin: insulin resistance to malignancy,” Clinica Chimica Acta, vol. 438, pp. 46–54, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. W. An, Y. Bai, S.-X. Deng et al., “Adiponectin levels in patients with colorectal cancer and adenoma: a meta-analysis,” European Journal of Cancer Prevention, vol. 21, no. 2, pp. 126–133, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. S. P. Gialamas, T. N. Sergentanis, C. N. Antonopoulos, N. Dessypris, G. P. Chrousos, and E. T. Petridou, “Circulating leptin levels and risk of colorectal cancer and adenoma: a case-control study and meta-analysis,” Cancer Causes and Control, vol. 24, no. 12, pp. 2129–2141, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. R. K. Joshi, W. J. Kim, and S.-A. Lee, “Association between obesity-related adipokines and colorectal cancer: a case-control study and meta-analysis,” World Journal of Gastroenterology, vol. 20, no. 24, pp. 7941–7949, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. R. K. Joshi and S.-A. Lee, “Obesity related adipokines and colorectal cancer: a review and meta-analysis,” Asian Pacific Journal of Cancer Prevention, vol. 15, no. 1, pp. 397–405, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. X. T. Xu, Q. Xu, J. L. Tong et al., “Meta-analysis: circulating adiponectin levels and risk of colorectal cancer and adenoma,” Journal of Digestive Diseases, vol. 12, no. 4, pp. 234–244, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Tulubas, R. Mete, M. Oznur, and B. Topcu, “The role of adipocytokines in colon cancer and adenomas,” Journal of Medical Biochemistry, vol. 33, no. 2, pp. 135–142, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Sălăgeanu, C. Tucureanu, L. Lerescu et al., “Serum levels of adipokines resistin and leptin in patients with colon cancer,” Journal of Medicine and Life, vol. 3, no. 4, pp. 416–420, 2010. View at Google Scholar · View at Scopus
  23. T. E. Nakajima, Y. Yamada, T. Hamano et al., “Adipocytokines as new promising markers of colorectal tumors: adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer,” Cancer Science, vol. 101, no. 5, pp. 1286–1291, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Kumor, P. Daniel, M. Pietruczuk, and E. Małecka-Panas, “Serum leptin, adiponectin, and resistin concentration in colorectal adenoma and carcinoma (CC) patients,” International Journal of Colorectal Disease, vol. 24, no. 3, pp. 275–281, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Kosova, T. Coskun, Y. Kaya, E. Kara, and Z. Ari, “Adipocytokine levels of colon cancer patients before and after treatment,” Bratislava Medical Journal, vol. 114, no. 7, pp. 394–397, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. G. Gonullu, H. Kahraman, A. Bedir, A. Bektas, and I. Yücel, “Association between adiponectin, resistin, insulin resistance, and colorectal tumors,” International Journal of Colorectal Disease, vol. 25, no. 2, pp. 205–212, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Danese, M. Montagnana, A. M. Minicozzi et al., “The role of resistin in colorectal cancer,” Clinica Chimica Acta, vol. 413, no. 7-8, pp. 760–764, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. L. Lu, L. Yi, M. Qiling, and H. Peizhen, “Study on serum leptin, adiponectin and resistin concentration in patients with colorectal cancer,” Journal of Medical Research, vol. 39, no. 9, pp. 78–80, 2010. View at Google Scholar
  29. D. Wägsäter, M. Mumtaz, S. Lofgren, A. Hugander, and J. Dimberg, “Resistin in human colorectal cancer: increased expression independently of resistin promoter −420C> G genotype,” Cancer Investigation, vol. 26, no. 10, pp. 1008–1014, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Otake, H. Takeda, S. Fujishima et al., “Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer,” World Journal of Gastroenterology, vol. 16, no. 10, pp. 1252–1257, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. G. Y. F. Ho, T. Wang, M. J. Gunter et al., “Adipokines linking obesity with colorectal cancer risk in postmenopausal women,” Cancer Research, vol. 72, no. 12, pp. 3029–3037, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Hillenbrand, J. Fassler, N. Huber et al., “Changed adipocytokine concentrations in colorectal tumor patients and morbidly obese patients compared to healthy controls,” BMC Cancer, vol. 12, article 545, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. D. F. Stroup, J. A. Berlin, S. C. Morton et al., “Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group,” JAMA, vol. 283, no. 15, pp. 2008–2012, 2000. View at Google Scholar
  34. G. A. Wells, B. Shea, D. O'Connell et al., “The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses,” http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp.
  35. S. P. Hozo, B. Djulbegovic, and I. Hozo, “Estimating the mean and variance from the median, range, and the size of a sample,” BMC Medical Research Methodology, vol. 5, article 13, 2005. View at Publisher · View at Google Scholar · View at Scopus
  36. T. Liu, G. Li, L. Li, and P. Korantzopoulos, “Association between C-reactive protein and recurrence of atrial fibrillation after successful electrical cardioversion: a meta-analysis,” Journal of the American College of Cardiology, vol. 49, no. 15, pp. 1642–1648, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. A. Tarkowski, J. Bjersing, A. Shestakov, and M. I. Bokarewa, “Resistin competes with lipopolysaccharide for binding to toll-like receptor 4,” Journal of Cellular and Molecular Medicine, vol. 14, no. 6, pp. 1419–1431, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. L. R. Howe, K. Subbaramaiah, C. A. Hudis, and A. J. Dannenberg, “Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer,” Clinical Cancer Research, vol. 19, no. 22, pp. 6074–6083, 2013. View at Publisher · View at Google Scholar · View at Scopus
  39. H. Mu, R. Ohashi, S. Yan et al., “Adipokine resistin promotes in vitro angiogenesis of human endothelial cells,” Cardiovascular Research, vol. 70, no. 1, pp. 146–157, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. N. Di Simone, F. Di Nicuolo, M. Sanguinetti et al., “Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes,” The Journal of Endocrinology, vol. 189, no. 3, pp. 691–699, 2006. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Qatanani, N. R. Szwergold, D. R. Greaves, R. S. Ahima, and M. A. Lazar, “Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice,” The Journal of Clinical Investigation, vol. 119, no. 3, pp. 531–539, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Mahmoudi, K. Karimi, M. Arkani et al., “Resistin -420C>G promoter variant and colorectal cancer risk,” The International Journal of Biological Markers, vol. 29, no. 3, pp. e233–e238, 2014. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Fernández-Sánchez, E. Madrigal-Santillán, M. Bautista et al., “Inflammation, oxidative stress, and obesity,” International Journal of Molecular Sciences, vol. 12, no. 5, pp. 3117–3132, 2011. View at Publisher · View at Google Scholar · View at Scopus
  44. E. Orgel and S. D. Mittelman, “The links between insulin resistance, diabetes, and cancer,” Current Diabetes Reports, vol. 13, no. 2, pp. 213–222, 2013. View at Publisher · View at Google Scholar · View at Scopus
  45. A. G. Renehan, M. Zwahlen, C. Minder, S. T. O'Dwyer, S. M. Shalet, and M. Egger, “Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis,” The Lancet, vol. 363, no. 9418, pp. 1346–1353, 2004. View at Publisher · View at Google Scholar · View at Scopus
  46. Y. Ikeda, H. Tsuchiya, S. Hama, K. Kajimoto, and K. Kogure, “Resistin affects lipid metabolism during adipocyte maturation of 3T3-L1 cells,” FEBS Journal, vol. 280, no. 22, pp. 5884–5895, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. O. A. Mojiminiyi and N. A. Abdella, “Associations of resistin with inflammation and insulin resistance in patients with type 2 diabetes mellitus,” Scandinavian Journal of Clinical and Laboratory Investigation, vol. 67, no. 2, pp. 215–225, 2007. View at Publisher · View at Google Scholar · View at Scopus
  48. M. Filková, M. Haluzík, S. Gay, and L. Šenolt, “The role of resistin as a regulator of inflammation: implications for various human pathologies,” Clinical Immunology, vol. 133, no. 2, pp. 157–170, 2009. View at Publisher · View at Google Scholar · View at Scopus
  49. S. Riondino, M. Roselli, R. Palmirotta, D. Della-Morte, P. Ferroni, and F. Guadagni, “Obesity and colorectal cancer: role of adipokines in tumor initiation and progression,” World Journal of Gastroenterology, vol. 20, no. 18, pp. 5177–5190, 2014. View at Publisher · View at Google Scholar · View at Scopus