Research Article

NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis

Table 1

Clinical baseline characteristics of prehypertensive patient population.

VariableStenosis <50%  Stenosis >50%  All patients p value (<50% versus >50%)

Age (yr)<0.001
Male132 (46.98)213 (72.20)345 (59.90)<0.001
BMI (kg/m2)0.292
DM (%)21 (7.47)55 (18.64)76 (13.19)0.001
Family history of HT (%)68 (24.20)65 (22.03)133 (23.09)0.538
Family history of DM (%)56 (19.93)115 (38.98)171 (29.69)<0.001
Serum potassium (mmol/L)0.002
Serum sodium (mmol/L)0.125
Urine potassium (mmol/L)0.686
Urine sodium (mmol/L)0.011
Uric acid (mmol/L)0.357
CRP0.013
LDL-C (mmol/L)<0.001
TG (mmol/L)0.457
PLT (109/L)0.660
LVEF (%)0.018
Smoking (%)111 (39.57)165 (55.83)276 (47.92)0.001
Alcohol (%)48 (17.08)75 (25.42)123 (21.35)0.015

BMI: body mass index; DM: diabetes mellitus; HT: hypertension; CRP: C-reactive protein; LDL: low-density lipoprotein; TG: triglycerides; PLT: platelet count; LVEF: left ventricular ejection fraction.