NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis

Table 2

Gene SNPs’ Hardy-Weinberg equilibrium and MAF among prehypertensive patients.

Genotype SNPs		⁢HWE			MAF	Detectability	Detectable rate (%)
		O(HET)	E(HET)	value
NOD2	rs1077861	0.297	0.306	0.613	0.188	566	98.26
	rs1861759	0.238	0.235	1.000	0.135	561	97.40
	rs2067085	0.111	0.124	0.067	0.066	567	98.44
	rs2111235	0.44	0.428	0.632	0.311	562	97.57
	rs3135499	0.348	0.368	0.326	0.243	566	98.26
	rs4785225	0.348	0.371	0.265	0.246	564	97.92
	rs7205423	0.398	0.407	0.704	0.284	566	98.26
	rs751271	0.352	0.375	0.220	0.25	567	98.44
	rs8056611	0.431	0.429	1.000	0.311	564	97.92
CARD8	rs2043211	0.555	0.498	0.038	0.472	564	97.92
	rs10405768	0.428	0.428	1.000	0.310	562	97.57
NLRP3	rs4612666	0.504	0.490	0.674	0.430	566	98.26
	rs1539019	0.544	0.499	0.098	0.474	566	98.26
	rs10754558	0.479	0.500	0.410	0.495	564	97.92
	rs10925027	0.489	0.499	0.756	0.473	564	97.92

HWE: Hardy-Weinberg equilibrium; O(HET): observed heterozygosity; E(HET): expected heterozygosity; MAF: minor allele frequency. value > 0.05, fit to HWE.