Research Article
NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis
Table 5
Multiple logistic regression of baseline characteristics and candidates allele genes.
| Variable | Univariate analysis | Multivariate analysis | value | OR | 95% CI | value |
| Gender | 0.000 | 6.157 | 2.790–13.584 | 0.000 | Age | 0.000 | 1.071 | 1.030–1.113 | 0.001 | Family history of HT | 0.657 | 0.705 | 0.333–1.491 | 0.360 | DM | 0.040 | 3.547 | 1.535–8.197 | 0.003 | Family history of CHD | 0.000 | 5.029 | 2.676–9.451 | 0.000 | SBP | 0.000 | 1.065 | 1.029–1.103 | 0.000 | Urine sodium | 0.087 | 0.997 | 0.992–1.001 | 0.092 | Serum potassium | 0.031 | 2.308 | 0.969–5.496 | 0.059 | LDL-C | 0.768 | 0.839 | 0.630–1.118 | 0.231 | Smoking | 0.112 | 0.756 | 0.354–1.613 | 0.469 | Alcohol | 0.098 | 1.280 | 0.620–2.643 | 0.504 | rs2111235 | 0.043 | 0.201 | 0.017–2.326 | 0.199 | rs10403848 | 0.031 | 0.907 | 0.351–2.345 | 0.840 | rs10754558 | 0.050 | 1.543 | 0.700–3.402 | 0.282 | rs1077861 | 0.133 | 1.352 | 0.716–2.553 | 0.353 | rs10925027 | 0.087 | 0.580 | 0.291–1.157 | 0.122 | rs1539019 | 0.191 | 1.289 | 0.565–2.939 | 0.546 | rs1861759 | 0.061 | 0.097 | 0.005–1.867 | 0.122 | rs2067085 | 0.109 | 0.519 | 0.214–2.657 | 0.495 | rs3135499 | 0.233 | 1.913 | 0.026–140.544 | 0.767 | rs4612666 | 0.074 | 1.241 | 0.601–2.564 | 0.559 | rs7205423 | 0.263 | 1.465 | 0.134–16.034 | 0.754 | rs751271 | 0.132 | 3.283 | 0.072–150.134 | 0.542 | rs8056611 | 0.098 | 1.501 | 0.109–20.728 | 0.762 | rs4785225 | 0.061 | 0.892 | 0.655–1.324 | 0.183 | rs10405768 | 0.078 | 0.679 | 0.312–1.569 | 0.514 |
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