Partial Portal Vein Arterialization Attenuates Acute Bile Duct Injury Induced by Hepatic Dearterialization in a Rat Model

Figure 4

PPVA protected completely dearterialized rat livers against necrosis 3 days after surgery. (a) The relationship between the biliary system and bile infarcts was assessed by injecting India ink into the CBD at a low pressure. The ink was detected in the centers of bile infarcts (asterisk), indicating that the biliary system communicated with the infarcts (H&E staining; magnification, 100x). (b) Coagulative necrosis of hepatocytes was detected in the BDI group on transmission electron microscopy. The tight junctions (arrows) and bile canaliculi (arrowhead) between necrotic hepatocytes were intact and not dilated (scale bars, 2 μm).

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