MicroRNA Profiling in Patients with Upper Tract Urothelial Carcinoma Associated with Balkan Endemic Nephropathy
Table 2
Differentially expressed microRNAs (determined with both GeneSpring software and R Bioconductor software) in BEN-UTUC and non-BEN-UTUC tissues when compared to normal kidney tissues.
BEN-UTUC
Log FC (GS)
P (GS)
Log FC (RB)
P (RB)
Non-BEN-UTUC
Log FC (GS)
P (GS)
Log FC (RB)
P (RB)
hsa-miR-205-5p ↑
9.184
6.598
0
hsa-miR-205-5p ↑
11.872
0.00135
8.798
0
hsa-miR-4322 ↑
5.808
0.006158
2.202
0.00076
hsa-miR-205-3p ↑
9.674
6.618
0
hsa-miR-99b-3p ↑
5.459
0.003146
2.144
0.00289
hsa-miR-224-5p ↑
7.268
0.015998
4.509
0.00474
hsa-miR-3620-3p ↑
5.073
0.008373
2.438
0.00195
hsa-miR-224-3p ↑
7.068
0.001425
3.278
0.02833
hsa-miR-373-5p ↑
4.349
0.008005
2.974
0.00092
hsa-miR-197-3p ↑
6.800
0.005539
2.211
0.01435
hsa-miR-3656 ↑
2.313
0.006171
2.294
0.00236
hsa-miR-182-5p ↑
6.717
0.002527
4.366
0.00474
hsa-miR-1290 ↑
2.168
0.006006
2.124
0.00374
hsa-miR-183-5p ↑
6.533
0.007597
4.422
0.00699
hsa-miR-30a-5p ↓
−3.299
0.043734
−3.265
0.02983
hsa-miR-96-5p ↑
6.422
0.031363
3.651
0.01527
hsa-miR-127-3p ↓
−4.790
0.036211
−2.104
0.0197
hsa-miR-203a-3p ↑
6.368
0.023474
4.518
0.00969
hsa-miR-154-5p ↓
−4.838
0.008468
−2.027
0.02172
hsa-miR-149-5p ↑
5.905
0.016274
3.306
0.01082
hsa-miR-141-3p ↑
3.792
0.00317
3.833
0.00207
hsa-miR-200c-3p ↑
3.655
0.00114
3.678
0.00028
hsa-miR-1260a ↑
3.306
0.035875
3.349
0.01684
hsa-miR-210-3p ↑
2.553
0.004245
2.566
0.02018
hsa-miR-663b ↓
−5.745
0.022896
−2.605
0.04726
↑: upregulated; ↓: downregulated; GS: GeneSpring; RB: R Bioconductor; FC: fold change; P: P value.
