Clinical Study

Effects of Early Continuous Venovenous Hemofiltration on E-Selectin, Hemodynamic Stability, and Ventilatory Function in Patients with Septic-Shock-Induced Acute Respiratory Distress Syndrome

Table 3

Hemodynamics, serum creatinine, and fluid balance between two groups at 0, 24, 48, and 72 h after initiation of treatment.

Hemodynamic variableECVVH ()non-ECVVH () value

Norepinephrine dose (μg/kg/min)
 0 h0.52
 24 h0.72
 48 h<0.001
 72 h<0.001
Serum creatinine (mg/dL)
 0 h0.67
 24 h0.03
 48 h<0.001
 72 h<0.001
Fluid balance (mL)
 0 h0.14
 24 h<0.001
 48 h<0.001
 72 h<0.001
ITBVI (mL/m2)
 0 h 0.52
 24 h0.48
 48 h0.07
 72 h0.23
CI (L/min/m2)
 0 h 0.34
 24 h0.36
 48 h0.45
 72 h0.54
MAP (mmHg)
 0 h 0.35
 24 h0.48
 48 h0.18
 72 h0.22
SVRI (dyns⋅s/(cm5⋅m2))
 0 h 0.67
 24 h0.77
 48 h0.31
 72 h0.56
EVLWI (mL/kg)
 0 h 0.63
 24 h0.84
 48 h0.01
 72 h0.04

CI = cardiac index, ECVVH = early continuous venovenous hemofiltration, EVLWI = extravascular lung water index, ITBVI = intrathoracic blood volume index, MAP = mean arterial pressure, and SVRI = systemic vascular resistance index.