Research Article
Identification of Novel RD1 Antigens and Their Combinations for Diagnosis of Sputum Smear−/Culture+ TB Patients
Table 1
Diagnostic performance of individual antigens.
| Antigens | Rv3871 | Rv3874 | Rv3875 | Rv3876 | Rv3879 |
| | | + | − | + | − | + | − | + | − | + | − |
| TB | 298 | 242 | 56 | 188 | 110 | 96 | 102 | 186 | 112 | 249 | 49 | Control | 95 | 24 | 71 | 5 | 90 | 12 | 83 | 14 | 81 | 16 | 79 |
| Sensitivity | | 81.21% | 63.09% | 32.21% | 62.42% | 83.56% | Specificity | | 74.74% | 94.74% | 87.37% | 85.26% | 83.16% | Youden | | 0.5595 | 0.5783 | 0.1958 | 0.4768 | 0.6672 | PPV | | 90.98% | 97.41% | 88.89% | 93.0% | 93.96% | NPV | | 55.91% | 45% | 44.86% | 41.97% | 61.72% |
|
|
PPV: positive predictive value, NPV: negative predictive value, and Youden: Youden index = sensitivity + specificity – 1.
|