Table 5: Diagnostic performance of the combination of Rv3871, Rv3876, and Rv3879 in different TB populations. The positive detection was defined as positive with at least two antigens.

Pos.Neg.SensitivitySpecificityYoudenPPVNPV

S+/C+117892876.07%90.53%0.666090.81%75.43%
S−/C+80681285%90.53%0.755388.3%87.76%
S−/C−101802179.21%90.53%0.697489.89%80.37%
Control95986

S+/−: sputum smear +/− TB, C+/−: sputum culture +/− TB, Pos.: positive, Neg.: negative.