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BioMed Research International
Volume 2016, Article ID 7508763, 4 pages
http://dx.doi.org/10.1155/2016/7508763
Research Article

Mean Platelet Volume in Mycobacterium tuberculosis Infection

1Department of Laboratory Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea
2Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea

Received 21 March 2016; Revised 30 May 2016; Accepted 1 June 2016

Academic Editor: Giulio Mengozzi

Copyright © 2016 Min Young Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Mean platelet volume (MPV) has been thought as a useful index of platelet activation. It is supposed that MPV is also associated with several inflammatory and infectious diseases. Korea still has a high incidence of tuberculosis (TB). The aim of this study was to investigate MPV as an inflammatory marker in TB patients. Materials and Methods. MPV were determined in 221 patients with TB and 143 individuals for control group. MPV was estimated by an Advia 2120 (Siemens Healthcare Diagnostics, Tarrytown, NY, USA). Results. In the TB patient group, a positive correlation was found between CRP and MPV. Age and MPV had a positive correlation in TB patient group. Conclusions. We conclude that there is a significant relation between MPV and inflammatory conditions. MPV can be an inflammatory marker to determine the disease activity in TB patients.