Research Article

Physiological Study on Association between Nicotinamide N-Methyltransferase Gene Polymorphisms and Hyperlipidemia

Table 3

Genotype effects and genetic models of rs1941404 variation.

ModelGenotypeCaseControlOR (95% CI)h

RecessiveCC117 (0.70)50 (0.30)2.432 (1.574, 3.534)0.000āˆ’0.54
TT+CT253 (0.49)263 (0.51)
DominantCC+CT274 (0.56)218 (0.44)1.244 (0.890, 1.738)0.202
TT96 (0.50)95 (0.50)
AdditiveCC117 (0.70)50 (0.38)2.316 (1.497, 3.581)0.000
TT96 (0.50)95 (0.59)
CodominantCT157 (0.48)168 (0.52)0.636 (0.470, 0.861)0.003
CC+TT213 (0.59)145 (0.41)

Case, the hyperlipidemia group; Ctrl, the control group; the values of the case and control are the number of individuals (frequency) from different genotypes; OR, odds ratio; CI, confidence interval; h (dominance degree) = , , OR of the codominant model; , OR of the additive model.